Cell Banking

Achieve a consistent, reproducible supply of cells that are fully characterized and fully compliant with Research, GLP, and GMP needs.

How CellPort
Improves Cell  Banking

Whether you’re producing monoclonal antibodies, vaccines, or other therapeutic proteins, CellPort helps streamline and automate cell culture processes, such as:

Cell Line Authentication
Working Cell Bank Preparation
Cell Line Characterization
Master Cell Bank Creation
Aseptic Techniques
Quality Control
Training and Education
From generic drug development to in vitro efficacy testing, cells aid in the end-to-end production of modern medicines. How biopharma R&D and manufacturing labs manage cells makes all the difference between getting FDA approval for commercial products, or not. CellPort helps your lab achieve more reproducible, ready-to-scale results. 
Built to optimize all upstream and downstream bioprocessing operations, CellPort helps biotech companies to experiment, develop, and manufacture – CellPort makes it easy to manage your end-to-end operations, from cell lineage tracing to product packaging and beyond. CellPort helps your lab scale commercial products that adhere to GLP and GMP standards.
For contract research and development labs to operate more efficiently, CellPort supports adherence to SOPs through automated time & scheduling, centralized communications, customized reporting, and a library of configurable protocols and assays.
Cellular Agriculture
Harvest a more plentiful cell culture – CellPort helps ensure a reliable and consistent supply of cells, with complete tracking and oversight into the scaffolds, serums, and cell culture environments. From R&D to GMP, CellPort delivers the tools you need to develop safer, purer cellular or acellular products.
Cellular Agriculture
Harvest a more plentiful cell culture – CellPort helps ensure a reliable and consistent supply of cells, with complete tracking and oversight into the scaffolds, serums, and cell culture environments. From R&D to GMP, CellPort delivers the tools you need to develop safer, purer cellular or acellular products.

Cell Line Authentication

Cell line misidentification or contamination leads to unreliable experimental results that waste valuable time and resources. Before creating a cell bank, cell lines must be properly identified and verified.

To create useful master cell banks (MCB) and working cell banks(WCB), the cell line must be identified with precision, typically completed via short tandem repeat (STR) or
whole-genome sequencing (WGS) testing to compare the DNA profiles of cell lines with a referential database. From there, to ensure the cell line remains pure and safe from contamination, labs typically conduct mycoplasma and sterility testing, along with regular viability assurance (i.e., regularly thawing a test vial for confirmation).

To prevent cross-contamination, labs should maintain separate equipment, practice strict aseptic techniques, and avoid shared workspaces or locations for each cell line. CellPort helps labs to schedule and track the completion of cell line authentication processes, and trace the lineage of cell lines over time.

Master Cell Bank Creation

Master Cell Bank Creation
Why create a master cell bank? – Master cell banks (MCB) ensure cell line integrity by preserving original cells that can be used if more cells need to be grown, or if cellular metobolics are altered due to excessive passaging or changes in media.

To create MCB, labs begin by selecting a cell of interest and expanding the cell line to an adequate scale; this is typically performed via cell culture. Once the cell density is satisfactory, the cells are cryopreserved in vials and placed in long-term storage. From there, labs characterize the cells through various means, documenting factors such as growth kinetics, morphology, and relevant genetic markers.

MCBs must be preserved under precise conditions with around-the-clock monitoring in a safe, secure location, and regularly thawed and cultured to assess viability, identity, and functionality over time – this is known as stability testing. CellPort’s automated workflows and assays help labs expedite the creation of MCBs, conduct regular testing, and ensure the ongoing safety and reliability of cell lines.

Working Cell Bank Preparation

Working Cell
Bank Preparation
Working cell banks (WCBs) are derived from the MCB and serve as the source of cells to be used in experimentation and production. Before usage, cells from the WCB must undergo tests to ensure that they are viable, that they accurately reflect the MCB characteristics, and that they have not been contaminated.

The use of a WCB enables consistency and reproducibility in cell lines, and this
two-tiered cell bank (MCB and WCB)
system also allows for well-characterized banks at significant cost savings. To help
get products to market faster, automated systems like CellPort streamline the WCB testing process and ensure that all steps are GMP compliant, with easy-to-use reporting tools that simplify regulatory audits.

Explore More Solutions

CellPort Features

Built by our scientists, for your scientists – Here’s how Cellport helps optimize cell culture and passaging.

CellPort Learning Hub

Browse our latest resources to learn more about how CellPort streamlines life sciences.

Products Videos

View all Videos
Time and Scheduling

Latest  Blogs

View all Blogs
European Pharmaceutical Manufacturer: Platform Technologies to Scale Up

Cell and gene therapies (CGTs) have emerged as revolutionary treatments for a wide range of diseases.

...Read more
CellPort Attending Bio-IT World: Leading the Digital Revolution in Life Sciences

The intersection of information technology and biotechnology has never been more crucial than it is today. As the biotech industry strives to harness the power of data to accelerate research and development, events like Bio-IT World become pivotal.

...Read more
CellPort Attending BPI West: Shaping the Future of Bioprocessing Together

In the rapidly evolving landscape of biopharmaceutical development, staying ahead of technological advancements and industry trends is not just beneficial—it's essential. CellPort is excited to attend the Bioprocessing International (BPI) West conference, March 11th through the 14th, in San Diego, where the bioprocessing community will converge.

...Read more
CellPort at Bioprocessing Summit Europe: Transforming the Future of Bioprocessing

As the bioprocessing industry continues to grow and evolve, staying at the forefront of technological advancements and innovative methods is more important than ever. CellPort is excited to attend the upcoming Bioprocessing Summit Europe, March 19th through the 21st, in Barcelona.

...Read more

Leadership Videos

View all Videos
Discover CellPort - The World's First All-in-One Cell Management Platform
CellPort Connect - CC 109: CROs, CDMOs, and Outsourcing
CellPort Connect - CC 108: How COVID Changed the Lab
CellPort Connect - CC 107: Improving Academic Training & Research
CellPort Connect - CC 106: Building Trust with Transparency
CellPort Connect - CC 105: Why Software Needs to Scale with You
CellPort Connect - CC 104: Artificial Intelligence and Clean Data
CellPort Connect - CC 102: Standardization by Design
CellPort Connect - CC 101: We Hear You
CellPort Connect - CC 103: Upskilling the Next Generation